Neural Responses to Auditory Oddball Paradigm in Rat Auditory Cortex
This interactive 3D visualization shows neuronal activity recorded from the auditory cortex of Sprague-Dawley rats in response to an auditory oddball paradigm and the administration of acetylcholine (ACh). Each point represents a neuron, color-coded according to cortical sub-regions (e.g., A1, AAF), with coordinates indicating the position within the cortex.
Stimuli consisted of tones presented with 90% (standard) vs. 10% (deviant) probability, allowing the assessment of novelty detection mechanisms in the auditory cortex.
This visualization reflects the modulatory effect of ACh on deviance detection. In a subset of experimental blocks, ACh was infused, showing a general trend toward decreased neuronal activity, with a more pronounced reduction in response to deviant tones. This supports the hypothesis that cholinergic signaling contributes to the cortical discrimination of behaviorally relevant auditory changes.
For more details on experimental design, data structure, and analysis tools, see the full dataset and code repository.
Neurons of the auditory cortex
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